About X11 and Wayland

I haven’t been up to date lately with VIM3 so I’m a bit confused. I’ve read that because of Mali X11 isn’t supported, only Wayland is supported. Does it mean that X11 based apps can’t run or do those apps run but aren’t hardware accelerated (aka sending the contexts to GPU to be renderd there instead of software rendered)?

I’m developing an app that for now only uses CPU software rendering, but I’d like to know if I can move to OpenGL or not if I choose VIM3 over the Edge-V. The framework I’m using only supports X11 not Wayland for Linux